特別講演会のお知らせ 2017.9.12
北海道支部 支部長 土谷 浩昭
この度下記の通り特別講演会が開催されます。
皆様におかれましては是非ご参加くださいますようご案内とお願いを申し上げます。
参加希望者は直接会場へお越しください。
記
日 時 ： 2017年 9月 25日（月） 11：00〜12：00
場 所 ： 北海道大学工学部 大会議室 Ａ1-17 （札幌市北区北１３条西８丁目）
講 演 ： 「Computational model of large-scale cell
migration and proliferation under mechanical control and biochemical
regulation: Cell motility, tissue patterning and wound healing」
Prof. Jie Liang, Professor, Richard and Loan Hill Department of Bioengineering,
The University of Illinois at Chicago, USA
Cells with different properties grow, divide, and interact with each other
and with Extra-Cellular Matrix (ECM) through mechanical forces, and signal
transduction, resulting in the formation of complex patterns that are important
for processes such as tissue development and wound healing. However, current computational cell models
are challenged to account for detailed changes in cellular shapes and physical
mechanics when studying thousands of migrating and interacting cells. We discuss recent development of
quantitative, models and algorithms, with focus on a novel dynamic cellular
finite, element (dyCelFEM) model. With
full account of changes in cellular, shapes, cellular topology, and celluar
mechanics, and with key, intra-cellular signaling networks embedded in
individual cells, we can study the full range of cell motion, from motilities
of individual cells to collective cell migrations. We discuss our recent findings on effects of
micro-patterned geometry on cell elongation and migration. We also described
results on examining the effects of biochemical and mechanical cues in
regulating cell migration and proliferation, and in controlling tissue patterning
in re-epithelialization of skin wound healing (Joint work with Jieling Zhao,
Youfang Cao, Wei Tian, Luisa DiPietro, and Margaret Gardel).
共催 ： 日本機械学会北海道支部バイオメカニクス懇話会
問い合わせ先：
Tel&Fax: 011-706-6424, Email: ohashi@eng.hokudai.ac.jp